Liverpool have made a remarkable start to the new season with four wins out of four, while Spurs saw their 100% record ended with a 2-1 defeat before the international break in the hands of Watford.
Mauricio Pochettino will be looking to recover from that shock loss but he will have to do so without Dele Alli and Hugo Lloris who have been sidelined with injuries.
This fixture certainly delivered last season, with nine goals across the two fixtures between Spurs and Liverpool.
Spurs dealt with their opponents (Liverpool) 4-1 last time they met at Wembley, before earning a 2-2 draw at Anfield later in the season with Mo Salah scoring twice.
Spurs will be boosted by the return of Heung-Min Son, but will find it difficult to come straight into the starting 11 in place of inform Lucas Moura..
Dejan Lovren remains out with injury and Simon Mignolet is a doubt though not likely to feature as well as Fabinho.
PREDICTED STARTING XI
Tottenham: Vorm; Alderweireld, Sanchez, Vertonghen; Trippier, Dier, Dembele, Rose; Eriksen; Moura, Kane.
Liverpool: Alisson; Alexander-Arnold, Gomez, Van Dijk, Robertson; Milner, Wijnaldum, Keita; Salah, Firmino, Mane.
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